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Patients who have an existing diagnosis of schizophrenia and require regular monitoring of medical status.

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Many of the remaining 25 percent suffer from a serious underlying brain disease that cannot be relieved through anticonvulsant therapy; others continue to have seizures because they refuse prescribed medication, they use it incorrectly, or their bodies do not reliably absorb the drugs.

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The effects of gabapentin, which was initially thought to have GABAergic effects, were compared with those of baclofen in a double-masked study including patients with APN.

Although mood symptoms and episodes must be present for a substantial portion of the total course of the illness, a diagnosis of schizoaffective disorder also requires that psychotic symptoms, such as delusions or hallucinations, have been present for a minimum of 2 weeks in the absence of an active mood disturbance.

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Several diseases, including MSA, CBD, and PSP, are sometimes referred to as "Parkinson's-plus" diseases because they have the symptoms of PD plus additional features.

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Recent studies support the earlier observations that motor fluctuations are part of the natural course of Parkinson's disease and are probably related to postsynaptic alterations in the striatum.

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In addition to a possible link to schizophrenia itself, many antipsychotic medications can raise blood sugar levels.

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Olanow, CW, Watts RL, Koller WC: An algorithm (decision tree) for the management of Parkinson's disease: treatment guidelines.

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Risk factors for increased dystonia in patients with include long disease duration and use of medication.

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